Allegra has no brain interference and no sedative effect1

For patients with tough allergy symptoms, that's a no-brainer

Every patient is different and can have a variety of symptoms.* Allegra provides powerful allergy relief for patients with itchy, watery eyes, itchy throat, runny nose, and sneezing. It starts working in 1 hour and doesn't cause drowsiness. That's why it’s the #1 allergist-recommended non-drowsy OTC antihistamine brand.

Allegra® Samples & Coupons

Order now

Learn more about:

No Brain Interference from Drowsiness
Efficacy
Allergy relief products
Frequently asked questions

No Brain Interference from Drowsiness

Allegra has no brain interference and no sedative effect1

  • Fexofenadine, the antihistamine molecule in Allegra is proven in several controlled studies to have 0% brain interference
  • Any brand that has less than 20% brain occupancy can claim to be non-drowsy
  • Brands like Zyrtec can cause drowsiness which can impact cognitive performance
  • Although Claritin can claim non-drowsy, the reality is that it can enter the brain and create a 13%-26% occupancy

Brain histamine H1-receptor occupancies of various antihistamines and classification for sedating actions. The occupancy data are represented as the mean +/- SD of measurements in positron emission tomography after oral single-dose administration of the drugs

Brain Receptor Occupancy of antihistamine medications

No Impact on Cognitive Function

Allegra does not impair cognitive function, psychomotor functions and performance1

Also, Allegra does not affect daytime sleepiness and performance1

A comparison chart displaying cognitive effects of antihistamines.

Efficacy

Allegra acts fast

It starts acting in 1 hour (applies for the first intake)1

The median reported onset of allergic rhinitis symptom relief for fexofenadine 180mg and 60mg is 1 hour for both dosages1

One hundred forty-six subjects who adequately responded to priming entered a single-dose placebo phase. Placebo-responders were disqualified from the study, leaving other subjects with adequate symptoms to be randomized and given a single dose of either fexofenadine HCl 120 mg, 60 mg or placebo, after 60 minutes of allergen exposure.

Allegra® Products

Get relief from the #1 allergist-recommended non-drowsy OTC antihistamine brand‡ for tough allergy symptoms* with Allegra® Allergy, Allegra-D®, and Children's Allegra® products.

Allergy Relief

Allergy & Congestion Relief

Relief for Kids

FAQs

*Symptoms include itchy, watery eyes; itchy nose or throat; rhinorrhea; and sneezing.
†See Drug Facts label. Use as directed.
‡Among single-ingredient branded OTC oral antihistamines.