What do you mean 0%?
Let’s be clear: zero is not nothing— it’s everything when it comes to antihistamines. The one with 0% brain interference that's non-drowsy? That’s the one you need to take seriously.
Picture this: zero brain fog from drowsiness means staying on point during that big meeting, keeping your plans intact, and no more dozing off halfway through the day, all while tackling allergy symptoms.
Sounds like a dream come true for anyone battling allergies, right?
What if we cut brain interference to 0%?
Some antihistamines cross a protective layer called the blood-brain barrier, making you drowsy. Allegra® is different—watch as it provides fast* allergy relief without crossing that barrier and without causing drowsiness. Why choose between relief and drowsiness?
Why Allegra®?
All the relief, 0% the interference from drowsiness, that’s why.
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Non-drowsy with 0% Brain Interference
The blood-brain barrier prevents certain things from entering, so your brain cells can keep functioning at their best without any unwanted interference. Our formula respects this boundary, ensuring your brain stays safe and uncompromised.
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Long-lasting
That's right, Allegra® provides up to 24 hours of non-drowsy relief without crossing the blood-brain barrier, so you can enjoy your day to the fullest knowing you’re covered right around the clock! That said, you should still use the old allergy excuse if you don’t want to go somewhere... we won’t tell.
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Fast-acting*
Places to be and people to see, we get it, life is full of unmissable experiences. Allegra® works quickly because of its active ingredient, which works fast* and relieves allergy symptoms without making you drowsy.
*Starts working in one hour
The science behind non-drowsy relief since 1996
Allegra®’s story began with a commitment to create allergy relief that is not only effective but also with less side effects like drowsiness.
When developing Allegra®, scientists focused on solving a major drawback of other antihistamines: drowsiness. Traditional allergy medications often cross the blood-brain barrier, triggering drowsiness and affecting alertness. The Allegra® team tackled this challenge by designing a unique oral antihistamine that avoids crossing this barrier, delivering fast-acting*, non-drowsy relief.
Allegra®’s active ingredient, fexofenadine, was engineered specifically to remain outside the central nervous system.
This innovation allows it to work directly on allergy symptoms without affecting your normal brain function. As a result, Allegra® offers effective symptom relief so you can live life fully.
Meet your match with Allegra®
Try our Allergy Symptom Checker to discover which Allegra® might be right for you.
Compare Allegra® to our competitors
Find out why Allegra® is the #1 recommended brand by allergists*.
*Among OTC oral antihistamines
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Allegra® Allergy
Zyrtec
Claritin
Benadryl
Fexofenadine
Cetirizine
Loratadine
Diphenhydramine
#1 allergist-recommended non-drowsy brand*
*Among OTC oral antihistaminesAllegra® stands out from Zyrtec by providing allergy relief without causing drowsiness.
Allegra® and Claritin may provide similar symptom relief, but Allegra® delivers the fastest** non-drowsy relief for allergy symptoms.
**Starts working in one hour. Applies to first dose only. Among non-drowsy single-ingredient OTC branded oral antihistaminesAllegra® provides allergy symptom relief for up to six times longer than Benadryl and boasts a non-drowsy antihistamine.
Doesn't Cross the Blood Brain Barrier Causing Drowsiness
#1 Allergist Recommended Non-Drowsy Brand
Non Drowsy
Works in one hour
24h relief
Available in gelcap
Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat)
-
Allegra® Hives
OTC Itch Relief Topicals
Fexofenadine
Various
Only FDA OTC medication on the market approved to reduce hives
With Allegra, you're treating your hives and itch at the source instead of treating symptoms topically.
Relieves Itch Due to Hives
FDA Approved for OTC use to reduce Hives at the source
24hrs
Non-drowsy
Preferred oral form
-
Allegra-D®
Zyrtec-D
Claritin-D
Benadryl Plus Congestion
Fexofenadine + pseudoephedrine
Cetirizine + pseudoephedrine
Loratadine + pseudoephedrine
Diphenhydramine + phenylephrine
Allegra® stands out from Zyrtec by providing allergy relief without causing drowsiness.
Allegra® and Claritin may provide similar symptom relief, but Allegra® delivers the fastest* non-drowsy relief for allergy symptoms.
Allegra® provides allergy symptom relief for up to six times longer than Benadryl and boasts a non-drowsy antihistamine.
Available in 24hr
Flexible 12hr Dosing
Works Fast
Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat)
Relieves Nasal and Sinus Congestion
-
Children's Allegra®
Zyrtec
Claritin
Benadryl
Fexofenadine
Cetirizine
Loratadine
Diphenhydramine
#1 allergist-recommended non-drowsy brand
Allegra® stands out from Zyrtec by providing allergy relief without causing drowsiness.
Allegra® and Claritin may provide similar symptom relief, but Allegra delivers fast, non-drowsy relief for allergy symptoms
Allegra® provides allergy symptom relief without causing drowsiness, unlike Benadryl.
Doesn't Cross the Blood Brain Barrier
#1 Allergist Recommended Non-Drowsy Children's Brand
Non Drowsy
Flexible 12hr Dosing
Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat)
- Ansotegui IJ et al. Curr Med Res Opin. 2024 Aug;40(8):1297-1309.
- Day JH, et al. Ann Allergy Asthma Immunol. 1997; 79: 533–540.
- Van Cauwenberge P et al. Clin Exp Allergy. 2000;30:891–899.
- Howarth PH et al. J Allergy Clin Immunol. 1999;104:927–933.