Proud to Give You Zero
0% brain interference due to drowsiness, that is.
What do you mean 0%?
Let’s be clear: zero is not nothing— it’s everything when it comes to antihistamines. Allegra means 0% brain interference. That’s the one you need to take seriously.
Picture this: zero brain fog from drowsiness means staying on point during that big meeting, keeping your plans intact, and no more dozing off halfway through the day, all while tackling allergy symptoms.
Sounds like a dream come true for anyone battling allergies, right?
What if we cut brain interference to 0%?
Some antihistamines cross a protective layer called the blood-brain barrier, making you drowsy. Allegra® is different—watch as it provides fast* allergy relief without crossing that barrier and without causing drowsiness. Why choose between relief and drowsiness?
Why Allegra®?
All the relief, 0% the interference from drowsiness, that’s why.
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Non-drowsy with 0% Brain Interference
Allegra®, provides non-drowsy allergy relief with 0% brain interference, relieving allergy symptoms like sneezing, runny nose and itchy eyes. Allergy relief doesn't have to be a choice between relief and drowsiness!
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Fast-acting*
That's right, Allegra® provides up to 24 hours of non-drowsy relief without crossing the blood-brain barrier, so you can enjoy your day to the fullest knowing you’re covered right around the clock! That said, you should still use the old allergy excuse if you don’t want to go somewhere... we won’t tell.
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Long-lasting
Places to be and people to see, we get it, life is full of unmissable experiences. Allegra® works quickly because of its active ingredient, which works fast* and relieves allergy symptoms without making you drowsy.
*Starts working in one hour
The science behind non-drowsy relief since 1996
Allegra®’s story began with a commitment to create allergy relief that is not only effective but also with less side effects like drowsiness.
When developing Allegra®, scientists focused on solving a major drawback of other antihistamines: drowsiness. Traditional allergy medications often cross the blood-brain barrier, triggering drowsiness and affecting alertness. The Allegra® team tackled this challenge by designing a unique oral antihistamine that avoids crossing this barrier, delivering fast-acting*, non-drowsy relief.
Allegra®’s active ingredient, fexofenadine, was engineered specifically to remain outside the central nervous system.
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This innovation allows it to work directly on allergy symptoms without affecting your brain. As a result, Allegra® offers effective symptom relief that keeps you alert and ready to live life fully.
Meet your match with Allegra®
Try our Allergy Symptom Checker to discover which Allegra® might be right for you.
Compare Allegra® to our competitors
Find out why Allegra® is the #1 recommended brand by allergists*.
*Among OTC oral antihistamines
Allegra® Allergy |
Zyrtec |
Claritin |
Benadryl |
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| Fexofenadine | Cetirizine | Loratadine | Diphenhydramine | ||
| #1 allergist-recommended non-drowsy brand* *Among OTC oral antihistamines |
Allegra® stands out from Zyrtec by providing allergy relief without causing drowsiness. | Allegra® and Claritin may provide similar symptom relief, but Allegra® delivers the fastest** non-drowsy relief for allergy symptoms. **Starts working in one hour. Applies to first dose only. Among non-drowsy single-ingredient OTC branded oral antihistamines |
Allegra® provides allergy symptom relief for up to six times longer than Benadryl and boasts a non-drowsy antihistamine. | ||
| #1 Allergist Recommended Non-Drowsy Brand | |||||
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| Non Drowsy | |||||
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| Works in one hour | |||||
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| 24h relief | |||||
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| Available in gelcap | |||||
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| Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat) | |||||
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Allegra® Hives |
OTC Itch Relief Topicals |
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| Fexofenadine | Various | ||
| Only FDA OTC medication on the market approved to reduce hives | With Allegra, you're treating your hives and itch at the source instead of treating symptoms topically. | ||
| Relieves Itch Due to Hives | |||
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| FDA Approved for OTC use to reduce Hives at the source | |||
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| 24hrs | |||
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| Non-drowsy | |||
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| Preferred oral form | |||
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Allegra-D® |
Zyrtec-D |
Claritin-D |
Benadryl Plus Congestion |
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| Fexofenadine + pseudoephedrine | Cetirizine + pseudoephedrine | Loratadine + pseudoephedrine | Diphenhydramine + phenylephrine | ||
| Allegra® stands out from Zyrtec by providing allergy relief without causing drowsiness. | Allegra® and Claritin may provide similar symptom relief, but Allegra® delivers the fastest* non-drowsy relief for allergy symptoms. | Allegra® provides allergy symptom relief for up to six times longer than Benadryl and boasts a non-drowsy antihistamine. | |||
| Available in 24hr | |||||
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| Flexible 12hr Dosing | |||||
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| Works Fast | |||||
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| Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat) | |||||
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| Relieves Nasal and Sinus Congestion | |||||
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Children's Allegra® |
Zyrtec |
Claritin |
Benadryl |
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| Fexofenadine | Cetirizine | Loratadine | Diphenhydramine | ||
| #1 allergist-recommended non-drowsy brand | Allegra® stands out from Zyrtec by providing allergy relief without causing drowsiness. | Allegra® and Claritin may provide similar symptom relief, but Allegra delivers fast, non-drowsy relief for allergy symptoms | Allegra® provides allergy symptom relief without causing drowsiness, unlike Benadryl. | ||
| #1 Allergist Recommended Non-Drowsy Children's Brand | |||||
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| Non Drowsy | |||||
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| Flexible 12hr Dosing | |||||
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| Relieves Allergy Symptoms (like sneezing, runny nose, itchy watery eyes and itchy nose or throat) | |||||
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Find your Allegra®
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References
- Ansotegui IJ et al. Curr Med Res Opin. 2024 Aug;40(8):1297-1309.
- Day JH, et al. Ann Allergy Asthma Immunol. 1997; 79: 533–540.
- Van Cauwenberge P et al. Clin Exp Allergy. 2000;30:891–899.
- Howarth PH et al. J Allergy Clin Immunol. 1999;104:927–933.